Discomfort or pain in the upper left abdomen
An enlarged spleen caused by leukemia sometimes results in abdominal discomfort or even sharp pain. “A patient that presented to me with chronic leukemia a few weeks ago, part of his spleen had died off from spleen enlargement,” says Dr. Levis. “It hurt like heck. It was a sharp pain in his abdomen.” Because the spleen is located in the upper-left quadrant of the abdomen, the discomfort usually occurs there. Don’t miss the 29 things you think cause cancer but actually don’t.